Annals of Thoracic Medicine Official publication of the Saudi Thoracic Society, affiliated to King Saud University
 
Search Ahead of print Current Issue Archives Instructions Subscribe e-Alerts Login 
Home Email this article link Print this article Bookmark this page Decrease font size Default font size Increase font size
CASE REPORT
Year : 2017  |  Volume : 12  |  Issue : 1  |  Page : 57-58

Herceptin responsive lung adenocarcinoma in the setting of bilateral synchronous lung primaries and breast carcinoma


Department of Cardiothoracic Surgery, St. James's Hospital, Dublin, Ireland

Correspondence Address:
Gerard J Fitzmaurice
Department of Cardiothoracic Surgery, St. James's Hospital, Dublin
Ireland
Login to access the Email id


DOI: 10.4103/1817-1737.182901

PMID: 28197225

Rights and Permissions

The incidence of human epidermal growth factor receptor 2 (Her-2) mutations in lung adenocarcinoma is approximately 3%; however, its significance in the management of these lung cancers remains under investigation. We describe an incidental but unique opportunity to evaluate the response to treatment with herceptin in a patient with bilateral synchronous lung primaries in conjunction with breast carcinoma. Interval imaging following surgical resection of the squamous cell carcinoma while on herceptin treatment delineated the radiological regression of the Her-2 positive lung adenocarcinoma. We feel that this case highlights the potential role for herceptin treatment in Her-2 positive lung adenocarcinomas and demonstrates the importance of screening for these mutations.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1055    
    Printed21    
    Emailed0    
    PDF Downloaded67    
    Comments [Add]    

Recommend this journal