Annals of Thoracic Medicine Official publication of the Saudi Thoracic Society, affiliated to King Saud University
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Year : 2010  |  Volume : 5  |  Issue : 3  |  Page : 171-173

Cilazapril-induced pleural effusion: A case report and review of the literature

1 Department of Chest Diseases, Baskent University School of Medicine, Ankara, Turkey
2 Department of Thoracic Surgery, Baskent University School of Medicine, Ankara, Turkey

Correspondence Address:
Elif Kupeli
Baskent University Department of Pulmonary Diseases, Fevzi Cakmak Cad, 5 sok, No 48, postal code 06490, Besevler, Ankara
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1817-1737.65043

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We describe an unusual case of lymphocytic pleural effusion associated with the use of cilazapril, a novel angiotensin-converting-enzyme inhibitor (ACEI). An 80-year-old male was prescribed cilazapril for hypertension. He subsequently presented with right chest pain and dry cough. He was found to have a lymphocytic pleural effusion on thoracentesis. Extensive workup, including open pleural biopsy, failed to reveal the etiology of the effusion. However, soon after the withdrawal of cilazapril, his clinical symptoms improved and the effusion disappeared. ACEI-induced pleural effusion has only been rarely reported. Drug-induced pleural effusion should be considered when formulating the differential diagnosis in a patient receiving ACEI.

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