Annals of Thoracic Medicine Official publication of the Saudi Thoracic Society, affiliated to King Saud University
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Year : 2012  |  Volume : 7  |  Issue : 3  |  Page : 171
Serum hepcidin and chronic obstructive pulmonary disease

1 Sanitation, Medical Academic Center, Bangkok, Thailand
2 Wiwanitkit House, Bangkhae, Bangkok, Thailand

Date of Web Publication21-Jul-2012

Correspondence Address:
Beuy Joob
Sanitation, Medical Academic Center, Bangkok
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1817-1737.98855

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How to cite this article:
Joob B, Wiwanitkit V. Serum hepcidin and chronic obstructive pulmonary disease. Ann Thorac Med 2012;7:171

How to cite this URL:
Joob B, Wiwanitkit V. Serum hepcidin and chronic obstructive pulmonary disease. Ann Thorac Med [serial online] 2012 [cited 2023 Feb 9];7:171. Available from:


The recent report on serum hepcidin and COPD is very interesting. [1] Duru et al. concluded that "serum hepcidin level may be a useful marker in COPD." [1] As Duru et al. proposed, a further confirmation is required. An important point is there is no complete assessment on hepatitis profile (such as hepatitis B, hepatitis C, etc.) needed. Also, some genetic disorders can also alter the hepcidin level that has to be ruled out. Thalassemia [2] as well as some other rare genetic mutations [3] should be ruled out. It is still very inconclusive to conclude for any usefulness of hepcidin as a new biomarker for COPD.

   References Top

1.Duru S, Bilgin E, Ardiç S. Hepcidin: A useful marker in chronic obstructive pulmonary disease. Ann Thorac Med 2012;7:31-5.  Back to cited text no. 1
2.Origa R, Galanello R. Pathophysiology of beta thalassaemia. Pediatr Endocrinol Rev 2011;8 (Suppl 2):263-70.  Back to cited text no. 2
3.Melis MA, Cau M, Congiu R, Sole G, Barella S, Cao A, et al. A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron. Haematologica 2008;93:1473-9.  Back to cited text no. 3

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Annals of Thoracic Medicine. 2012; 7(3): 171-172


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