| CASE REPORT |
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| Year : 2014 | Volume
: 9
| Issue : 1 | Page : 39-41 |
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A rare case of alpha 1-antitrypsin deficiency associated with hypogammaglobulinemia and recurrent pulmonary thrombosis
Raghav Gupta1, Srilekha Sridhara1, John A Wood2
1 Department of Internal Medicine, Allergy and Immunology, St. Luke's Hospital, Chesterfield, MO, USA
2 Department of Pulmonology, Allergy and Immunology, St. Luke's Hospital, Chesterfield, MO, USA
Correspondence Address:
Raghav Gupta
14463, Greencastle Drive, Apt#6, Chesterfield, MO 63017
USA
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/1817-1737.124442
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Alpha 1-antitrypsin (AAT) belongs to the family of serpins (serine protease inhibitors). Loop sheet polymerization is the pathology behind serpinopathies which encompasses AAT, anti-thrombin III and neuroserpin deficiency. To the best of our knowledge, we report the first case of alpha 1-antitrypsin deficiency associated with hypogammaglobulinemia and recurrent pulmonary thrombosis without any concomitant use of drugs. |
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