Annals of Thoracic Medicine Official publication of the Saudi Thoracic Society, affiliated to King Saud University
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Year : 2014  |  Volume : 9  |  Issue : 4  |  Page : 203-208

Pressure-controlled versus volume-controlled ventilation during one-lung ventilation in elderly patients with poor pulmonary function

Department of Anesthesiology, Tumor Hospital of Guangxi Medical University, Nanning, China

Correspondence Address:
Linghui Pan
Department of Anesthesiology, Tumor Hospital of Guangxi Medical University, 71# Hedi Load, Nanning 530021
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Source of Support: The following grants and foundations supported this work: Research grant no. 81060008 from the National Natural Science Foundation of China and Research grant no. 200203 from the Bureau of Health, Guangxi, and Research grant no. 2010GXNSFB013087 from Natural Science Foundation of Guangxi Province of China.,, Conflict of Interest: None

DOI: 10.4103/1817-1737.140125

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Objective: The aim was to investigate the effects of two different ventilatory strategies: Pressure-controlled ventilation (PCV) versus volume-controlled ventilation (VCV) in elderly patients with poor pulmonary function during one-lung ventilation (OLV). Patients and Methods: The patients were enrolled into the study having poor pulmonary function (forced expiratory volume in 1 s <1.5 L) and undergoing radical resection of pulmonary carcinoma requiring at least 2 h of OLV. Patients were respectively allocated to VCV group and PCV group. The intraoperative data, arterial, and mixed venous blood gases were obtained at baseline, 20, 40, 60, 80, 100 and 120 min after OLV and end of surgery. The postoperative data had been recorded and arterial gas measurements were performed at 6, 12 and 24 h after surgery in Intensive Care Unit. Results: Comparison of the VCV group and PCV group, PaO 2 and P(A-a)O 2 were higher and dead space to tidal volume was lower in the PCV group (P < 0.05) after the point of OLV +60, Ppeak was higher in the VCV group (P < 0.05). There were significant advantages in PCV groups with regard to the PaO 2 of three points in postoperation, the duration of postoperative ventilation duration, intensive care duration of stay and the days stay in hospital after surgery. Conclusions: The use of PCV compared with VCV during OLV in elderly patients with poor pulmonary function has significant advantages of intraoperative and postoperative oxygenation and it might be a factor, which can beneficial to postoperative recovery.

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