Annals of Thoracic Medicine Official publication of the Saudi Thoracic Society, affiliated to King Saud University
 
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GUIDELINES
Year : 2014  |  Volume : 9  |  Issue : 5  |  Page : 47-55

Saudi Guidelines on the Diagnosis and Treatment of Pulmonary Hypertension: Pulmonary hypertension due to left heart disease


1 Department of Cardiology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
2 Pulmonary Medicine, Department of Medicine, Prince Sultan Medical Military City, Riyadh, Saudi Arabia
3 Department of Cardiology, Fondazione IR IRCCS Policlinico San Matteo, Pavia, Italy
4 Department of Cardiac Sciences, King Fahd Cardiac Center, King Saud University, Riyadh, Saudi Arabia

Correspondence Address:
Tarek Kashour
MD, Professor of Cardiology, Department of Cardiac Sciences, King Fahd Cardiac Center, King Saud University, Riyadh
Saudi Arabia
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1817-1737.134026

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Pulmonary hypertension (PH) due to left heart disease is the most common cause of pulmonary hypertension in the western world. It is classified as WHO PH group II. Different pathophysiologic abnormalities may take place in this condition, including pulmonary venous congestion and vascular remodeling. Despite the high prevalence of WHO group 2 PH, the major focus of research on PH over the past decade has been on WHO group 1 pulmonary arterial hypertension (PAH). Few investigators have focused on WHO group 2 PH; consequently, the pathophysiology of this condition remains poorly understood, and no specific therapy is available. Clinical and translational studies in this area are much needed and have the potential to positively affect large numbers of patients. In this review, we provide a detailed discussion upon the pathophysiology of the disease, the recent updates in classification, and the diagnostic and therapeutic algorithms.


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