Annals of Thoracic Medicine
ORIGINAL ARTICLE
Year
: 2019  |  Volume : 14  |  Issue : 2  |  Page : 141--147

Association of preoperative systemic corticosteroid therapy with surgical outcomes in chronic obstructive pulmonary disease patients


Samer Abou Arbid1, Habib El-Khoury1, Faek Jamali2, Hani Tamim1, Hassan Chami1 
1 Department of Internal Medicine, American University of Beirut Medical Center, Lebanon, USA
2 Department of Surgery, American University of Beirut Medical Center, Lebanon, USA

Correspondence Address:
Dr. Hassan Chami
American University of Beirut Medical Center, Riad El Solh 11-0236, Beirut, Lebanon
USA

BACKGROUND: Chronic obstructive pulmonary disease (COPD) patients are at an increased risk of postoperative pulmonary complications (PPCs). The purpose of this study is to evaluate the risks and benefits associated with preoperative steroids in COPD patients. METHODS: The National Surgical Quality Improved Program database was used to identify 92 COPD patients who underwent surgery at the American University of Beirut Medical Center between 2009 and 2013. COPD was diagnosed based on postbronchodilator forced expiratory volume in 1 s to forced vital capacity ratio <0.7 and a history of smoking. The exposure of interest was preoperative systemic corticosteroid therapy. The primary outcomes were PPCs and wound complications. Cardiac and urinary complications along with unplanned readmission or reoperation and death were also evaluated. RESULTS: Overall 42.4% of patients received preoperative systemic corticosteroids. Postoperative wound complications were significantly more frequent in COPD patients who received preoperative systemic corticosteroids compared to patients who did not (10.3% vs. none, respectively, P = 0.03). However, PPCs were not significantly different between patients who received preoperative systemic corticosteroids and patients who did not (17.9% vs. 13.2%, respectively, P = 0.53). There were no significant differences in the secondary outcomes. CONCLUSIONS: This study suggests that preoperative administration of systemic corticosteroids in stable COPD patients is associated with an increased risk of postoperative wound complications but may not reduce PPCs.


How to cite this article:
Arbid SA, El-Khoury H, Jamali F, Tamim H, Chami H. Association of preoperative systemic corticosteroid therapy with surgical outcomes in chronic obstructive pulmonary disease patients.Ann Thorac Med 2019;14:141-147


How to cite this URL:
Arbid SA, El-Khoury H, Jamali F, Tamim H, Chami H. Association of preoperative systemic corticosteroid therapy with surgical outcomes in chronic obstructive pulmonary disease patients. Ann Thorac Med [serial online] 2019 [cited 2022 Jul 7 ];14:141-147
Available from: https://www.thoracicmedicine.org/article.asp?issn=1817-1737;year=2019;volume=14;issue=2;spage=141;epage=147;aulast=Arbid;type=0