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Figure 3: A 120 s epoch of N2 sleep from our patient's continuous positive airway pressure titration study. At the highest tested pressure of 8 cm H2O, vagus nerve stimulation-induced flow limitation events continue to occur, accompanied in supine by SaO2 desaturations of 3% (in this example, SaO2 falls from 98% to 95%; box), suggesting only partial response of vagus nerve stimulation-induced sleep disordered breathing to continuous positive airway pressure

Figure 3: A 120 s epoch of N2 sleep from our patient's continuous positive airway pressure titration study. At the highest tested pressure of 8 cm H<sub>2</sub>O, vagus nerve stimulation-induced flow limitation events continue to occur, accompanied in supine by SaO<sub>2</sub> desaturations of 3% (in this example, SaO<sub>2</sub> falls from 98% to 95%; box), suggesting only partial response of vagus nerve stimulation-induced sleep disordered breathing to continuous positive airway pressure